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Adult Pneumococcal Vaccination — 21vPCV (Capvaxive) Clinician Reference

Adult pneumococcal vaccination — 21vPCV (Capvaxive)

Clinician reference for the National Immunisation Program adult pneumococcal schedule. Eligibility, repeat vaccination, co-administration, pregnancy, contraindications. Information only — confirm against the Australian Immunisation Handbook before administering.

From 1 July 2026: The 21-valent pneumococcal conjugate vaccine (21vPCV), Capvaxive®, replaces Prevenar 13® and Pneumovax 23® on the National Immunisation Program for adults. A single dose replaces the former Prevenar 13 + Pneumovax 23 sequence. The funded age for non-Indigenous adults is lowered from 70 to 65, and from 50 to 25 for Aboriginal and Torres Strait Islander adults.
📋 Source (verified June 2026): Reference for registered health professionals. Not prescribing advice — clinical decisions remain with the treating practitioner.

Key points

Eligibility — who is recommended a pneumococcal vaccine

Adults 65 and over

A single dose of Capvaxive® — recommended and NIP-funded.

ATSI adults 25 and over

A single dose of Capvaxive® — recommended and NIP-funded.

Adults 18+ with a risk condition

A single dose of Capvaxive® at diagnosis — see the Handbook risk-conditions table for the eligible list.

Repeat vaccination

For patients with prior pneumococcal vaccination, the rules collapse to a small number of scenarios. All Capvaxive® doses below are NIP-funded for the indicated patient group.

PatientRecommendation
65+ with a prior pneumococcal vaccine (any type)One dose of Capvaxive® at least 12 months after the last dose.
ATSI 25+ with a prior pneumococcal vaccineOne dose of Capvaxive® at least 12 months after the last dose.
18+ with a risk condition + prior pneumococcal vaccineOne dose of Capvaxive® at least 12 months after the last dose.
18–64 who already received Capvaxive® for a risk conditionNo further dose at 65.
ATSI 18–24 who already received Capvaxive® for a risk conditionNo further dose at 25.
65+ or ATSI 25+ who had Capvaxive® and then develops a risk conditionNo further dose.
Child given a dose of Prevenar 20® for a risk condition before 18One dose of Capvaxive® at age 18, NIP-funded.

For complex histories (immunocompromised patients, multiple prior doses, transplant recipients), check the pneumococcal chapter of the Handbook and AIR before administering.

Co-administration with other vaccines

Adults can receive Capvaxive® at the same time as, or separately from, other vaccines — including zoster (Shingrix), seasonal influenza, RSV, and COVID-19. The Department of Health notes potential advantages of co-administration: maximising coverage and timely receipt. Separate injection sites; the Handbook recommends a minimum 2.5 cm gap between sites. See the vaccine co-administration checker for paired-vaccine guidance.

Pregnancy and breastfeeding

Pneumococcal vaccines are not routinely recommended for pregnant women. Women of child-bearing age with a risk condition for pneumococcal disease are normally recommended to receive a vaccine either before a planned pregnancy, or as soon as practicable after delivery. Breastfeeding women can receive pneumococcal vaccines.

Contraindications

The only contraindications to pneumococcal vaccines are anaphylaxis after:

Side effects

Common side effects include mild pain at the injection site, fatigue and headaches, typically lasting a few days and resolving without treatment. Serious side effects, such as severe allergic reaction, are rare. Capvaxive® was found to be safe in adults across clinical trials. Source: Department of Health adult pneumococcal program advice, June 2026.

Administration errors and AIR

Check the Australian Immunisation Register (AIR) before administering any pneumococcal vaccine to confirm prior doses. Report all immunisations to AIR. Notify all adverse events and vaccine administration errors through the reporting mechanisms in your state or territory. For Handbook guidance on vaccine administration errors, see the Australian Immunisation Handbook. AIR information for providers: servicesaustralia.gov.au/hpair.

State and territory health department contacts
  • ACT: 02 5124 9800
  • NSW: 1300 066 055
  • NT: 08 8922 8044
  • QLD: contact your local Public Health Unit
  • SA: 1300 232 272
  • TAS: 1800 671 738
  • VIC: immunisation@health.vic.gov.au
  • WA: 08 9321 1312

Source: Department of Health adult pneumococcal program advice, June 2026.

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