Total and interpret the International Restless Legs Syndrome Study Group Rating Scale (IRLS) — the standard measure of RLS symptom severity. Enter the score (0–4) for each of the 10 items you recorded, and this tool returns the 0–40 total and severity band.
| Total score | Severity |
|---|---|
| 0 | None |
| 1–10 | Mild |
| 11–20 | Moderate |
| 21–30 | Severe |
| 31–40 | Very severe |
Restless legs syndrome (RLS, also called Willis–Ekbom disease) is a clinical diagnosis — there is no confirmatory blood test or scan. The International RLS Study Group consensus criteria require all five of these features:
The IRLS is used after diagnosis to rate how severe the symptoms are.
The IRLS is a clinician-administered, 10-item scale (each item 0–4, total 0–40) covering symptom intensity, frequency, sleep disturbance, daytime impact and mood. It is the standard severity outcome in RLS treatment trials. In practice it's most useful as a baseline you can repeat — to follow severity over time and gauge response to treatment. A total of around 15 or more is commonly used in studies to define moderate-to-severe RLS.
Brain iron deficiency is central to RLS, so iron studies belong in the workup even when someone isn't anaemic. Take a morning, fasting serum ferritin and transferrin saturation (TSAT).
RLS uses a higher ferritin target than ordinary iron deficiency. Consensus guidelines (IRLSSG / AASM) suggest considering iron treatment when ferritin is ≤75 µg/L or TSAT <20%, and reserving IV iron for ferritin between 75 and 100. Remember ferritin is an acute-phase reactant and can read falsely high with inflammation. Treatment choices rest with the clinician and current guidelines.
Augmentation is the main long-term complication of dopaminergic treatment for RLS: symptoms paradoxically worsen — starting earlier in the day, becoming more intense, or spreading to other body parts. It's a leading cause of treatment failure, and low ferritin is associated with it (correcting iron can lower the risk). Repeating the IRLS over time helps you pick up worsening severity that may signal augmentation rather than simple disease progression.